[Oxidative stress in metabolic syndrome and nonalcoholic steatohepatitis. Is it possible a role for vitamins in clinical practice?]

Recenti Prog Med. 2006 Jan;97(1):1-5.
[Article in Italian]

Abstract

Metabolic syndrome (MS) is a worldwide medical problem characterized by a cluster of cardiovascular risk factors and metabolic modifications involving peripheral insulin resistance. Nonalcoholic steatohepatitis (NASH) represents the liver expression of this pathological condition. Both MS and NASH are characterized by proinflammatory status and increased oxidative stress. According this, we aimed to review the literature for considering a possible role for vitamins as therapeutical support in MS and NASH.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Adult
  • Animals
  • Antioxidants / administration & dosage
  • Antioxidants / therapeutic use*
  • Cells, Cultured
  • Clinical Trials as Topic
  • Endothelial Cells / drug effects
  • Endothelial Cells / metabolism
  • Fatty Liver / complications
  • Fatty Liver / metabolism*
  • Female
  • Folic Acid / administration & dosage
  • Folic Acid / therapeutic use
  • Hepatitis / complications
  • Hepatitis / metabolism*
  • Homocysteine / pharmacology
  • Humans
  • Insulin Resistance
  • Male
  • Metabolic Syndrome / complications
  • Metabolic Syndrome / diagnosis
  • Metabolic Syndrome / drug therapy*
  • Metabolic Syndrome / metabolism*
  • Oxidative Stress*
  • Rats
  • Risk Factors
  • Silybin
  • Silymarin / therapeutic use
  • Time Factors
  • Vitamin B 12 / administration & dosage
  • Vitamin B 12 / therapeutic use
  • Vitamin D / administration & dosage
  • Vitamin D / therapeutic use
  • Vitamins / administration & dosage
  • Vitamins / therapeutic use*

Substances

  • Antioxidants
  • Silymarin
  • Vitamins
  • Homocysteine
  • Vitamin D
  • Silybin
  • Folic Acid
  • Vitamin B 12