Long-term outcome of intralesional injection of triamcinolone acetonide for the treatment of keloid scars in Asian patients

Scand J Plast Reconstr Surg Hand Surg. 2006;40(2):111-6. doi: 10.1080/02844310500430003.

Abstract

We studied the long-term outcome of injection of triamcinolone acetonide into keloid scars in Asian patients. Between 1985 and 2003, we treated 109 keloid scars in 94 patients by injecting 1 to 10?mg of triamcinolone acetonide depending on the size of the lesion at four week intervals. There was little morbidity. Thirty-one patients gave up treatment within 10 injections because of pain and lack of immediate improvement. Improvement in subjective symptoms was seen in 52 of the remaining 63 patients (82%). In objective symptoms, fair or better results were seen in 40 of 63 (63%), and good or better results in 25 of 63 (39%). The treatment method required 20-30 injections over three to five years. Although we did not achieve as good results as other authors, we think it was safer because we used a smaller dose of a steroid.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Asian People
  • Child
  • Child, Preschool
  • Cicatrix / drug therapy*
  • Cicatrix / etiology
  • Female
  • Glucocorticoids / therapeutic use*
  • Humans
  • Infant
  • Infant, Newborn
  • Injections, Intralesional / statistics & numerical data
  • Keloid / complications
  • Keloid / drug therapy*
  • Male
  • Middle Aged
  • Pain / drug therapy
  • Pain / etiology
  • Pruritus / drug therapy
  • Pruritus / etiology
  • Treatment Outcome
  • Triamcinolone Acetonide / therapeutic use*

Substances

  • Glucocorticoids
  • Triamcinolone Acetonide