The purpose of this study was to compare the diagnostic yield of repetitive radial nerve stimulation (RNS) while recording from extensor indicis proprius (EIP) to other commonly used muscle-nerve combinations in patients with myasthenia gravis (MG). Radial RNS with recording from EIP was performed in 20 controls and 20 patients with MG. It revealed an abnormal decrement at rest in 35% of patients compared to 11% with ulnar nerve stimulation, 64% with spinal accessory nerve stimulation, and 74% with facial nerve stimulation. Radial-EIP RNS is a reliable technique in the evaluation of MG and appears more sensitive than ulnar nerve RNS.