The Duarte (N314D) variant in the GALT gene has no effect on in vitro fertilization outcome

Shigeki Yoshida; Jo Steele; John Koninckx; Enda McVeigh; Stephen Kennedy

doi:10.1016/j.fertnstert.2005.07.1307

The Duarte (N314D) variant in the GALT gene has no effect on in vitro fertilization outcome

Fertil Steril. 2006 Feb;85(2):502-4. doi: 10.1016/j.fertnstert.2005.07.1307.

Authors

Shigeki Yoshida¹, Jo Steele, John Koninckx, Enda McVeigh, Stephen Kennedy

Affiliation

¹ Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom. [email protected]

PMID: 16595241
DOI: 10.1016/j.fertnstert.2005.07.1307

Abstract

We assessed the effect of the Duarte (N314D) variant in the GALT gene on in vitro fertilization outcome measures. Our data do not definitely exclude variants in the GALT gene as factors influencing outcome, but the lack of suggestive evidence makes it difficult to justify a larger, more definitive study.

MeSH terms

Adult
Arginine
Asparagine
Aspartic Acid
Case-Control Studies
Female
Fertilization
Fertilization in Vitro*
Gene Frequency
Genetic Variation*
Genotype
Glutamine
Humans
Infertility / genetics*
Infertility / therapy*
Mutation
Pregnancy
Pregnancy Rate
Treatment Outcome
UDPglucose-Hexose-1-Phosphate Uridylyltransferase / genetics*

Substances

Glutamine
Aspartic Acid
Asparagine
Arginine
UDPglucose-Hexose-1-Phosphate Uridylyltransferase