Gadolinium-chlorin is potentially a new tumor specific MRI contrast agent

Arch Pharm Res. 2006 Mar;29(3):188-90. doi: 10.1007/BF02969390.

Abstract

In this study, a newly-synthesized metalloporphyrin, Gd-chlorin (PB Chlorin), was investigated by using a simple tissue phantom to test its efficacy as an MRI contrast agent. This study demonstrated the potential activity of Gd-chlorin as not only a MRI contrast agent, but also as a PDT photosensitizer by using a simple tissue phantom and conducting a very brief MRI experiment.

MeSH terms

  • Contrast Media / chemical synthesis*
  • Echo-Planar Imaging / instrumentation
  • Echo-Planar Imaging / methods*
  • Metalloporphyrins / chemical synthesis*
  • Phantoms, Imaging
  • Photosensitizing Agents / chemical synthesis

Substances

  • Contrast Media
  • Metalloporphyrins
  • Photosensitizing Agents
  • gadolinium-chlorin