[LMP-420, a new therapeutic approach for cerebral malaria?]

MeSH terms

• Animals
• Anti-Inflammatory Agents, Non-Steroidal / pharmacology
• Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
• Antimalarials / pharmacology
• Antimalarials / therapeutic use*
• Boron Compounds / pharmacology
• Boron Compounds / therapeutic use*
• Cell Adhesion / drug effects
• Cells, Cultured / drug effects
• Cells, Cultured / metabolism
• Chemokine CCL2 / antagonists & inhibitors
• Chemokine CCL2 / metabolism
• Child, Preschool
• Depression, Chemical
• Drug Evaluation, Preclinical
• Endothelial Cells / drug effects
• Endothelial Cells / metabolism
• Female
• Gene Expression Regulation / drug effects
• Humans
• I-kappa B Proteins / metabolism
• Infant
• Infant, Newborn
• Intercellular Adhesion Molecule-1 / biosynthesis
• Intercellular Adhesion Molecule-1 / genetics
• Malaria, Cerebral / drug therapy*
• Malaria, Falciparum / drug therapy
• Male
• NF-kappa B / metabolism
• Phosphorylation / drug effects
• Plasmodium falciparum / physiology
• Pregnancy
• Pregnancy Complications, Infectious / drug therapy
• Protein Processing, Post-Translational / drug effects
• Purines / pharmacology
• Purines / therapeutic use*
• Receptors, Cell Surface / drug effects
• Th1 Cells / metabolism
• Tumor Necrosis Factor-alpha / antagonists & inhibitors*
• Vascular Cell Adhesion Molecule-1 / biosynthesis
• Vascular Cell Adhesion Molecule-1 / genetics