Polymicrobial keratomycosis in a three-year-old child

Ocul Immunol Inflamm. 2006 Apr;14(2):129-31. doi: 10.1080/09273940500328487.

Abstract

Purpose: To describe a previously unreported case of polymicrobial mycotic keratitis caused by an association between Candida lusitaniae, C. parapsilosis, and Geotrichum candidum.

Methods: A three-year-old child with an antecedent trauma with vegetable matter and a prolonged use of corticosteroid eyedrops developed fungal keratitis.

Results: The isolates of the corneal scraping using Sabaraud dextrose agar grew C. lusitaniae, C. parapsilosis, and G. candidum. After topical 0.2% and systemic fluconazole treatment, the corneal lesion resolved with no recurrence.

Conclusions: Corneal trauma with vegetables and the indiscriminate use of corticosteroids are important risk factors for mycotic keratitis. A combination of topical 0.2% and systemic fluconazole therapy was effective in the treatment of this mycotic association. This is the first report of fungal keratitis caused by C. lusitaniae and G. candidum.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Candida / isolation & purification*
  • Candidiasis / diagnosis
  • Candidiasis / drug therapy
  • Candidiasis / microbiology*
  • Child, Preschool
  • Eye Infections, Fungal / diagnosis
  • Eye Infections, Fungal / drug therapy
  • Eye Infections, Fungal / microbiology*
  • Follow-Up Studies
  • Geotrichosis / diagnosis
  • Geotrichosis / drug therapy
  • Geotrichosis / microbiology*
  • Geotrichum / isolation & purification*
  • Humans
  • Keratitis / diagnosis
  • Keratitis / drug therapy
  • Keratitis / microbiology*

Substances

  • Antifungal Agents