Abstract
In a patient with a rapidly progressive neurological condition with ataxia and cognitive complaints, Creutzfeldt-Jakob disease (CJD) is often high in the differential, particularly when there is an elevated CSF 14-3-3 protein level. We present a case of anti-glutamic acid decarboxylase antibody (anti-GAD65) positive cerebellar ataxia associated with cognitive complaints and elevated CSF 14-3-3 protein.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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14-3-3 Proteins / cerebrospinal fluid
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Antibodies / metabolism*
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Cerebellar Ataxia / diagnosis*
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Cerebellar Ataxia / etiology
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Cerebellar Ataxia / metabolism*
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Creutzfeldt-Jakob Syndrome / diagnosis*
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Diagnosis, Differential
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Female
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Glutamate Decarboxylase / immunology*
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Humans
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Middle Aged
Substances
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14-3-3 Proteins
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Antibodies
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Glutamate Decarboxylase