High anxiety is associated with an increased risk of death in an older tri-ethnic population

J Clin Epidemiol. 2006 May;59(5):534-40. doi: 10.1016/j.jclinepi.2005.10.008. Epub 2006 Jan 23.

Abstract

Background and objectives: The health consequences of anxiety in late life have not been adequately investigated. We sought to examine the association between anxiety and death in an older tri-ethnic population.

Methods: A longitudinal population-based study of 506 older noninstitutionalized non-Hispanic Whites, non-Hispanic Blacks, and Hispanics aged 75 years or older from Galveston County.

Results: Average age was 80.8 (SD 4.4) and 50.8% were women. Older non-Hispanic Whites (21.6%) reported the highest prevalence of anxiety, followed by Hispanics (12.4%) and non-Hispanic blacks (11.3%) (P=.0001). High anxiety was significantly associated with an increased hazard of all cause death (HR 1.52; 95% CI 1.02, 2.28) and cardiovascular death (HR 1.90; 95% CI 1.06, 3.36); and was associated with an increased hazard of cancer death (HR 2.38; 95% CI 0.88, 6.45) during 5-years of follow-up.

Conclusion: There is a high prevalence of anxiety in late life. Our results indicate an association between anxiety and increased risk of death in persons aged 75 and older.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living
  • Aged
  • Aged, 80 and over
  • Aging / psychology*
  • Anxiety / psychology*
  • Attitude to Death*
  • Black People / psychology
  • Black or African American
  • Cardiovascular Diseases / mortality
  • Cause of Death
  • Epidemiologic Methods
  • Female
  • Hispanic or Latino / psychology
  • Humans
  • Male
  • Neoplasms / mortality
  • Socioeconomic Factors
  • Texas / epidemiology
  • White People / psychology