Negative results of an Italian Group for Mesothelioma (G.I.Me.) pilot study of single-agent imatinib mesylate in malignant pleural mesothelioma

Cancer Chemother Pharmacol. 2007 Jan;59(1):149-50. doi: 10.1007/s00280-006-0243-4. Epub 2006 Apr 25.
No abstract available

Publication types

  • Clinical Trial
  • Letter

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / therapeutic use*
  • Benzamides
  • Disease Progression
  • Female
  • Humans
  • Imatinib Mesylate
  • Male
  • Mesothelioma / drug therapy*
  • Middle Aged
  • Pilot Projects
  • Piperazines / adverse effects
  • Piperazines / therapeutic use*
  • Pleural Neoplasms / drug therapy*
  • Protein Kinase Inhibitors / adverse effects
  • Protein Kinase Inhibitors / therapeutic use*
  • Pyrimidines / adverse effects
  • Pyrimidines / therapeutic use*
  • Receptors, Platelet-Derived Growth Factor / drug effects
  • Stem Cell Factor / metabolism
  • Treatment Failure

Substances

  • Antineoplastic Agents
  • Benzamides
  • Piperazines
  • Protein Kinase Inhibitors
  • Pyrimidines
  • Stem Cell Factor
  • Imatinib Mesylate
  • Receptors, Platelet-Derived Growth Factor