Use of 2-tracer PET to diagnose gastrointestinal stromal tumour and pheochromocytoma in patients with Carney triad and neurofibromatosis type 1

Per Bümming; Bengt Nilsson; Jens Sörensen; Ola Nilsson; Håkan Ahlman

doi:10.1080/00365520500434838

Use of 2-tracer PET to diagnose gastrointestinal stromal tumour and pheochromocytoma in patients with Carney triad and neurofibromatosis type 1

Scand J Gastroenterol. 2006 May;41(5):626-30. doi: 10.1080/00365520500434838.

Authors

Per Bümming¹, Bengt Nilsson, Jens Sörensen, Ola Nilsson, Håkan Ahlman

Affiliation

¹ Lundberg Laboratory for Cancer Research, Department of Surgery, Sahlgrenska University Hospital, Göteborg, Sweden.

PMID: 16638708
DOI: 10.1080/00365520500434838

Abstract

There is rapid evolution in the functional imaging of tumours. In two patients with concomitant pheochromocytoma and gastrointestinal stromal tumour (GIST), previously unrecognized tumours were visualized by combined 2-tracer positron emission tomography (PET), which also provided precise information about tumour type. PET imaging led to radical resection and the diagnoses were histopathologically confirmed. GISTs from the Carney patient and the patient with neurofibromatosis type 1 (NF1) both lacked KIT mutations.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adrenal Gland Neoplasms / diagnostic imaging*
Female
Fluorodeoxyglucose F18
Gastrointestinal Stromal Tumors / diagnostic imaging*
Humans
Leiomyoma / complications*
Male
Mediastinal Neoplasms / complications*
Middle Aged
Neurofibromatosis 1 / complications*
Neurofibromatosis 1 / diagnostic imaging
Paraganglioma, Extra-Adrenal / complications*
Pheochromocytoma / diagnostic imaging*
Positron-Emission Tomography / methods*
Radiopharmaceuticals

Substances

Radiopharmaceuticals
Fluorodeoxyglucose F18