Intracranial complications of pediatric sinusitis

Otolaryngol Head Neck Surg. 2006 May;134(5):733-6. doi: 10.1016/j.otohns.2005.12.001.

Abstract

Objective: To study intracranial extension of pediatric sinusitis, an infrequent but potentially fatal complication.

Study design and setting: Ten-year retrospective review at a tertiary children's hospital identified 21 cases of intracranial complications of sinusitis.

Results: Thirteen males and eight females with mean age of 13.3 years were identified. Overall 18 of 21 (81%) exhibited abscess formation, most commonly epidural. Only 3 of 21 (14%) had meningitis alone. All but 4 patients were managed surgically, requiring craniotomy in 13 of 21 (61.9%) and endoscopic sinus surgery (ESS) in 10 of 21 (48%). Seven patients (33%) required multiple operations during admission. Nineteen patients (90%) had a total of 30 organisms cultured. Oral flora was observed in 12 of 21 (57%). Polymicrobial infections, seen in 9 of 21 (43%), were significantly associated with the need for craniotomy (P=0.02). Mean hospital stay was 15 days, and mean length of IV antibiotic was 5 weeks.

Conclusions: Intracranial complications of pediatric sinusitis often require craniotomy. Oral flora and polymicrobial infections were prominent in this series.

Ebm rating: C-4.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / therapeutic use
  • Brain Abscess / etiology
  • Brain Abscess / surgery
  • Central Nervous System Bacterial Infections / etiology*
  • Central Nervous System Bacterial Infections / surgery
  • Child
  • Child, Preschool
  • Craniotomy
  • Empyema, Subdural / etiology
  • Empyema, Subdural / surgery
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Meningitis / drug therapy
  • Meningitis / etiology
  • Prognosis
  • Retrospective Studies
  • Sinus Thrombosis, Intracranial / etiology
  • Sinus Thrombosis, Intracranial / surgery
  • Sinusitis / complications*
  • Sinusitis / drug therapy

Substances

  • Anti-Bacterial Agents