Metabolic consequences of exercise-associated autonomic failure

Exerc Sport Sci Rev. 2006 Apr;34(2):72-6. doi: 10.1249/00003677-200604000-00006.

Abstract

Type I diabetes mellitus patients who tightly control blood glucose levels toward normal have increased frequency of hypoglycemia, a major barrier to physical activity. This article presents the hypothesis that dysfunctional autonomic regulation of metabolism after recent bouts of exercise or hypoglycemia contributes to exercise-induced hypoglycemia in these patients.

MeSH terms

  • Autonomic Nervous System / metabolism*
  • Autonomic Nervous System / physiology
  • Autonomic Nervous System Diseases / etiology
  • Autonomic Nervous System Diseases / metabolism*
  • Blood Glucose / metabolism
  • Diabetes Mellitus, Type 1 / metabolism*
  • Diabetes Mellitus, Type 1 / physiopathology
  • Epinephrine / biosynthesis
  • Exercise / physiology*
  • Female
  • Humans
  • Hypoglycemia / metabolism*
  • Hypoglycemia / physiopathology
  • Male
  • Norepinephrine / biosynthesis
  • United States

Substances

  • Blood Glucose
  • Norepinephrine
  • Epinephrine