Post radiation sarcoma (malignant fibrous histiocytoma) of the cervical spine following ependymoma (a case report)

J Neurooncol. 1991 Dec;11(3):263-8. doi: 10.1007/BF00165536.

Abstract

A case is reported of a 36 y/o man treated with radiation therapy for cervical cord ependymoma who developed malignant fibrous histiocytoma of the cervical spine 15 years later. Pathology revealed the sarcoma adjacent to the recurrent ependymoma. Post-radiation sarcomas following treatment of central nervous system malignancies is discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Astrocytoma / diagnosis
  • Cervical Vertebrae*
  • Combined Modality Therapy
  • Dacarbazine / administration & dosage
  • Dexamethasone / administration & dosage
  • Diagnostic Errors
  • Doxorubicin / administration & dosage
  • Ependymoma / diagnosis
  • Ependymoma / radiotherapy*
  • Ependymoma / surgery
  • Histiocytoma, Benign Fibrous / drug therapy
  • Histiocytoma, Benign Fibrous / etiology*
  • Histiocytoma, Benign Fibrous / pathology
  • Histiocytoma, Benign Fibrous / surgery
  • Humans
  • Laminectomy
  • Male
  • Neoplasms, Radiation-Induced / etiology*
  • Neoplasms, Radiation-Induced / pathology
  • Neoplasms, Second Primary / etiology*
  • Radiotherapy, High-Energy / adverse effects*
  • Spinal Cord Neoplasms / diagnosis
  • Spinal Cord Neoplasms / radiotherapy*
  • Spinal Cord Neoplasms / surgery
  • Spinal Neoplasms / drug therapy
  • Spinal Neoplasms / etiology*
  • Spinal Neoplasms / pathology
  • Spinal Neoplasms / surgery

Substances

  • Dacarbazine
  • Dexamethasone
  • Doxorubicin