Intact pks15/1 in non-W-Beijing Mycobacterium tuberculosis isolates

Emerg Infect Dis. 2006 May;12(5):772-4. doi: 10.3201/eid1205.051208.

Abstract

To determine whether intact pks15/1 is unique to the W-Beijing family, we investigated 147 Mycobacterium tuberculosis strains with different IS6110 genotypes. Intact pks15/1 was found in 87.8% of cerebrospinal fluid and 84.9% of sputum isolates. It was found not only in W-Beijing strains (approximate, equals 97%) but also in other genotypes (38.5%-100%).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Cerebrospinal Fluid / microbiology
  • DNA, Bacterial / analysis*
  • Genotype
  • Humans
  • Molecular Sequence Data
  • Mycobacterium tuberculosis / classification
  • Mycobacterium tuberculosis / genetics*
  • Mycobacterium tuberculosis / isolation & purification
  • Polymorphism, Restriction Fragment Length*
  • Sequence Alignment
  • Sputum / microbiology

Substances

  • DNA, Bacterial