Acanthamoeba encephalitis in patient with systemic lupus, India

Charudatt G Shirwadkar; Rohini Samant; Milind Sankhe; Ramesh Deshpande; Shigeo Yagi; Frederick L Schuster; Rama Sriram; Govinda S Visvesvara

doi:10.3201/eid1206.060087

Acanthamoeba encephalitis in patient with systemic lupus, India

Emerg Infect Dis. 2006 Jun;12(6):984-6. doi: 10.3201/eid1206.060087.

Authors

Charudatt G Shirwadkar¹, Rohini Samant, Milind Sankhe, Ramesh Deshpande, Shigeo Yagi, Frederick L Schuster, Rama Sriram, Govinda S Visvesvara

Affiliation

¹ P.D. Hinduja National Hospital and Research Centre, Mumbai, India.

Abstract

We report a fatal case of encephalitis caused by Acanthamoeba in a 24-year-old woman from India with systemic lupus erythematosus. Diagnosis was made by identification of amebas in brain sections by immunofluorescence analysis and confirmed by demonstrating Acanthamoeba mitochondrial 16S rRNA gene DNA in brain tissue sections.

Publication types

Case Reports

MeSH terms

Acanthamoeba / genetics
Acanthamoeba / growth & development*
Adult
Amebiasis / complications*
Amebiasis / diagnosis
Amebiasis / pathology
Animals
Central Nervous System Protozoal Infections / complications*
Central Nervous System Protozoal Infections / diagnosis
Central Nervous System Protozoal Infections / pathology
DNA, Protozoan / chemistry
DNA, Protozoan / genetics
Encephalitis / complications*
Encephalitis / diagnosis
Encephalitis / pathology
Fatal Outcome
Female
Histocytochemistry
Humans
India
Lupus Erythematosus, Systemic / parasitology*
Polymerase Chain Reaction

Substances

DNA, Protozoan