Antiretroviral drug resistance and routine therapy, Cameroon

Emerg Infect Dis. 2006 Jun;12(6):1001-4. doi: 10.3201/eid1206.050860.

Abstract

Among 128 patients routinely receiving highly active antiretroviral therapy in an HIV/AIDS outpatient clinic in Cameroon, 16.4% had drug resistance after a median of 10 months. Of these, 12.5% had resistance to nucleoside reverse transcriptase inhibitors (NRTIs), 10.2% to non-NRTIs, and 2.3% to protease inhibitors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Amino Acid Sequence
  • Antiretroviral Therapy, Highly Active / methods*
  • Base Sequence
  • Cameroon / epidemiology
  • Cross-Sectional Studies
  • Drug Resistance, Viral / genetics*
  • Female
  • Genotype
  • HIV Infections / drug therapy*
  • HIV Infections / epidemiology
  • HIV-1 / genetics
  • HIV-1 / growth & development*
  • Humans
  • Male
  • Middle Aged
  • Phylogeny
  • RNA, Viral / chemistry
  • RNA, Viral / genetics
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sequence Analysis, DNA
  • Serotyping
  • Urban Population

Substances

  • RNA, Viral