Lethal paradoxical cerebral vein thrombosis due to suspicious anticoagulant rodenticide intoxication with chlorophacinone

F Papin; F Clarot; C Vicomte; J M Gaulier; C Daubin; F Chapon; E Vaz; B Proust

doi:10.1016/j.forsciint.2006.04.003

Lethal paradoxical cerebral vein thrombosis due to suspicious anticoagulant rodenticide intoxication with chlorophacinone

Forensic Sci Int. 2007 Mar 2;166(2-3):85-90. doi: 10.1016/j.forsciint.2006.04.003. Epub 2006 May 23.

Authors

F Papin¹, F Clarot, C Vicomte, J M Gaulier, C Daubin, F Chapon, E Vaz, B Proust

Affiliation

¹ Forensic Department, Caen University Hospital, Caen, France.

PMID: 16716547
DOI: 10.1016/j.forsciint.2006.04.003

Abstract

Superwarfarin exposure is a growing health problem, described in many countries. The authors report a case of suspicious chlorophacinone poisoning with a problematic diagnosis. They review the literature and discuss particularities of anticoagulant rodenticide intoxication, as well as the apparent contradiction between anticoagulant intoxication and lethal thrombosis.

Publication types

Case Reports
Review

MeSH terms

Adult
Brain Edema / chemically induced
Brain Edema / pathology
Cerebral Infarction / chemically induced
Cerebral Infarction / pathology
Coma / chemically induced
Fatal Outcome
Female
Forensic Pathology
Forensic Toxicology
Hematuria / chemically induced
Humans
Indans / analysis
Indans / poisoning*
Intracranial Thrombosis / chemically induced*
Intracranial Thrombosis / pathology
Rodenticides / analysis
Rodenticides / poisoning*
Subarachnoid Hemorrhage / chemically induced
Subarachnoid Hemorrhage / pathology

Substances

Indans
Rodenticides
chlorophacinone