Nephrotic-range proteinuria following pamidronate therapy in a patient with metastatic breast cancer: mitochondrial toxicity as a pathogenetic concept?

Am J Kidney Dis. 2006 Jun;47(6):1075-80. doi: 10.1053/j.ajkd.2006.02.189.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / adverse effects*
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use*
  • Biopsy
  • Bone Neoplasms / drug therapy*
  • Bone Neoplasms / secondary
  • Breast Neoplasms / pathology
  • Carcinoma, Ductal, Breast / pathology
  • Diphosphonates / adverse effects*
  • Diphosphonates / pharmacology
  • Diphosphonates / therapeutic use*
  • Dose-Response Relationship, Drug
  • Epithelium / physiopathology
  • Female
  • Glomerulosclerosis, Focal Segmental / chemically induced
  • Glomerulosclerosis, Focal Segmental / complications
  • Glomerulosclerosis, Focal Segmental / pathology
  • Glomerulosclerosis, Focal Segmental / physiopathology
  • Humans
  • Kidney / drug effects
  • Kidney / pathology
  • Kidney / physiopathology
  • Kidney / ultrastructure
  • Middle Aged
  • Mitochondria / drug effects*
  • Mitochondria / physiology
  • Mitochondria / ultrastructure
  • Neoplasm Metastasis / drug therapy
  • Pamidronate
  • Proteinuria / chemically induced*
  • Proteinuria / etiology

Substances

  • Antineoplastic Agents
  • Diphosphonates
  • Pamidronate