Abstract
Nocardiosis is an infection caused by a soil-borne aerobic micro-organism. The pathogen is most commonly introduced in humans by inhalation into the respiratory tract. This infection may be transient and subclinical or may result in an acute or chronic bronchopulmonary process. Although an unusual cause of pulmonary infection in immunocompentent individuals, human nocardiosis is now documented more often in patients whose cell-mediated immunity is compromised by immunosuppression from comorbid disease or as a result of modern medical intervention. The diagnosis is often elusive unless a high index of suspicion is maintained. We present a patient with localized pulmonary nocardiosis who was immunosuppressed by virtue of a myeloproliferative disorder.
MeSH terms
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Aged
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Anti-Infective Agents / administration & dosage
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Anti-Infective Agents / therapeutic use
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Biopsy, Needle
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Bronchoscopy
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Follow-Up Studies
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Humans
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Immunocompromised Host
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Lung / microbiology
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Lung / pathology
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Lung Diseases* / diagnosis
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Lung Diseases* / diagnostic imaging
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Lung Diseases* / drug therapy
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Lung Diseases* / microbiology
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Lung Diseases* / pathology
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Male
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Neural Tube Defects / complications
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Neural Tube Defects / drug therapy
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Nocardia Infections* / diagnosis
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Nocardia Infections* / diagnostic imaging
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Nocardia Infections* / drug therapy
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Nocardia Infections* / microbiology
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Nocardia Infections* / pathology
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Nocardia asteroides* / isolation & purification
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Primary Myelofibrosis / complications
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Primary Myelofibrosis / drug therapy
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Radiography, Thoracic
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Solitary Pulmonary Nodule / diagnosis
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Solitary Pulmonary Nodule / etiology*
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Time Factors
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Tomography, X-Ray Computed
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Treatment Outcome
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Trimethoprim, Sulfamethoxazole Drug Combination / administration & dosage
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Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use
Substances
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Anti-Infective Agents
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Trimethoprim, Sulfamethoxazole Drug Combination