Abstract
Pig-tailed macaques (Macaca nemestrina) naturally infected with West Nile virus were monitored from 1999 to 2005 to determine virus-specific antibody seroconversion, prevalence, and persistence. Antibodies persisted for up to 36 months, as detected by epitope-blocking enzyme-linked immunosorbent and hemagglutination inhibition assays. Exposure to cocirculating St. Louis encephalitis virus was evaluated by Western blotting and immunofluorescence assays.
Publication types
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Comparative Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antibodies, Viral / blood*
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Blotting, Western / methods
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Encephalitis Virus, St. Louis / immunology*
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Encephalitis, St. Louis / blood*
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Encephalitis, St. Louis / immunology
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Encephalitis, St. Louis / veterinary
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Encephalitis, St. Louis / virology
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Enzyme-Linked Immunosorbent Assay / methods
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Follow-Up Studies
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HIV Seropositivity
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Hemagglutination Inhibition Tests / methods
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Macaca nemestrina / virology*
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Prevalence
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Retrospective Studies
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West Nile Fever / blood*
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West Nile Fever / epidemiology
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West Nile Fever / immunology
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West Nile Fever / veterinary
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West Nile virus / immunology*