Absence of CYP2B6 promoter -82T>C mutation in Chinese as an additional factor for slow metabolism of drugs commonly used in infections

Eur J Clin Pharmacol. 2006 Jul;62(7):585-6. doi: 10.1007/s00228-006-0163-6. Epub 2006 Jun 13.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / pharmacokinetics*
  • Aryl Hydrocarbon Hydroxylases / genetics*
  • Asian People / genetics*
  • China
  • Cytochrome P-450 CYP2B6
  • Cytosine
  • Humans
  • Infections / drug therapy*
  • Infections / genetics
  • Mutation / genetics*
  • Oxidoreductases, N-Demethylating / genetics*
  • Pharmacogenetics
  • Polymorphism, Single Nucleotide / genetics*
  • Promoter Regions, Genetic / genetics*
  • Thymine

Substances

  • Anti-Infective Agents
  • Cytosine
  • Aryl Hydrocarbon Hydroxylases
  • CYP2B6 protein, human
  • Cytochrome P-450 CYP2B6
  • Oxidoreductases, N-Demethylating
  • Thymine