Abstract
Musashi1 is a highly conserved protein found in neural progenitor cells. We examined the expression dynamics of Musashi1 in conjunction with other representative neural progenitor antigenic determinants (Ki-67 and nestin) during 8 different stages of the developing human fetal germinal matrix. Our results indicate that Musashi1 is a useful marker for immature cells in periventricular areas inhabited by stem cells, progenitor cells, and differentiating cells.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Brain / embryology*
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Brain Chemistry*
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Cerebral Ventricles / chemistry
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Cerebral Ventricles / embryology
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Fetal Development
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Gestational Age
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Glial Fibrillary Acidic Protein / analysis
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Humans
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Immunohistochemistry
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Intermediate Filament Proteins / analysis
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Ki-67 Antigen / analysis
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Nerve Tissue Proteins / analysis
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Nerve Tissue Proteins / biosynthesis*
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Nestin
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RNA-Binding Proteins / biosynthesis*
Substances
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Glial Fibrillary Acidic Protein
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Intermediate Filament Proteins
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Ki-67 Antigen
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MSI1 protein, human
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NES protein, human
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Nerve Tissue Proteins
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Nestin
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RNA-Binding Proteins