Abstract
This study evaluated the natural history of acute tonsillopharyngitis associated with atypical bacterial infections, showing that Mycoplasma pneumoniae and Chlamydia pneumoniae organisms are frequently found in children with acute tonsillopharyngitis. The study also demonstrated, for what we believe to be the first time, that, unless adequately treated, acute tonsillopharyngitis associated with infection with M. pneumoniae and C. pneumoniae may have a negative outcome with a high risk of recurrence of respiratory illness.
Publication types
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Acute Disease
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Adolescent
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Anti-Bacterial Agents / therapeutic use
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Antibodies, Bacterial
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Azithromycin / therapeutic use
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Child
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Child, Preschool
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Chlamydophila Infections / drug therapy*
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Chlamydophila pneumoniae / immunology*
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Disease Progression
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Female
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Humans
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Infant
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Male
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Mycoplasma Infections / drug therapy*
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Mycoplasma pneumoniae / immunology*
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Pharyngeal Diseases / drug therapy*
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Pharyngeal Diseases / microbiology*
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Pharyngitis / drug therapy
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Pharyngitis / microbiology
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Recurrence
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Tonsillitis / drug therapy
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Tonsillitis / microbiology
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Treatment Outcome
Substances
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Anti-Bacterial Agents
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Antibodies, Bacterial
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Azithromycin