Abstract
Platelets are key players in arterial thrombosis and have become important targets in the primary and secondary prevention of atherothrombosis. Antiplatelet drugs are primarily directed against platelets and inhibit platelet activation by a number of different mechanisms. They are used for the prevention and treatment of thrombotic processes, especially in the arterial vascular system. Antiplatelet drugs in clinical use and experimental drugs are discussed.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Aspirin / pharmacology
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Cyclooxygenase Inhibitors / pharmacology*
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Drug Design*
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Humans
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Platelet Aggregation Inhibitors / chemistry
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Platelet Aggregation Inhibitors / pharmacology*
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Platelet Membrane Glycoprotein IIb / drug effects*
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Purinergic Antagonists*
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Pyridines / pharmacology
Substances
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Cyclooxygenase Inhibitors
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Platelet Aggregation Inhibitors
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Platelet Membrane Glycoprotein IIb
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Purinergic Antagonists
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Pyridines
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thienopyridine
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Aspirin