A novel complex insertion/deletion mutation in the XPC DNA repair gene leads to skin cancer in an Iraqi family

J Invest Dermatol. 2006 Nov;126(11):2542-4. doi: 10.1038/sj.jid.5700452. Epub 2006 Jun 22.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Base Sequence
  • Child
  • DNA Mutational Analysis
  • DNA Repair / genetics*
  • DNA-Binding Proteins / genetics*
  • Female
  • Gene Expression
  • Humans
  • Iraq
  • Male
  • Molecular Sequence Data
  • Mutagenesis, Insertional
  • Mutation
  • Pedigree
  • Polymorphism, Genetic
  • RNA, Messenger / analysis
  • Sequence Deletion
  • Skin Neoplasms / genetics*
  • Xeroderma Pigmentosum / genetics*
  • Xeroderma Pigmentosum / pathology

Substances

  • DNA-Binding Proteins
  • RNA, Messenger
  • XPC protein, human