Rate of progression of valvular aortic stenosis in patients undergoing dialysis

J Am Soc Echocardiogr. 2006 Jul;19(7):914-8. doi: 10.1016/j.echo.2006.01.026.

Abstract

Background: In patients undergoing dialysis, aortic valve calcification and aortic stenosis are frequently found. However, the rate of progression of aortic stenosis is still unclear.

Methods: In all, 55 consecutive patients undergoing dialysis were followed up by echocardiography for a period of 12 months. Patients were divided into two groups: noncalcification (no or mildly calcified aortic valve) and calcification (moderate or heavily calcified aortic valve).

Results: The rate of progression of maximum aortic jet velocity and degression of aortic valve area were more rapid in calcification group than in noncalcification group (0.37 +/- 0.36 m/s and 0.17 +/- 0.29 m/s, P = .027; 0.17 +/- 0.15 cm2 and 0.04 +/- 0.07 cm2, P < .001, respectively).

Conclusions: The degree of aortic stenosis progressed more rapidly in patients undergoing dialysis with aortic valve calcification than without aortic valve calcification.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Aged
  • Aortic Valve Stenosis / diagnostic imaging*
  • Aortic Valve Stenosis / epidemiology*
  • Calcinosis / diagnostic imaging*
  • Calcinosis / epidemiology*
  • Causality
  • Comorbidity
  • Dialysis / statistics & numerical data*
  • Disease Progression
  • Female
  • Humans
  • Incidence
  • Japan / epidemiology
  • Male
  • Outcome Assessment, Health Care / methods
  • Prognosis
  • Risk Assessment / methods*
  • Risk Factors
  • Severity of Illness Index*
  • Ultrasonography