Toxin gene content of the Lyon methicillin-resistant Staphylococcus aureus clone compared with that of other pandemic clones

Tristan Ferry; Michèle Bes; Olivier Dauwalder; Hélène Meugnier; Gerard Lina; Françoise Forey; François Vandenesch; Jerome Etienne

doi:10.1128/JCM.00430-06

Toxin gene content of the Lyon methicillin-resistant Staphylococcus aureus clone compared with that of other pandemic clones

J Clin Microbiol. 2006 Jul;44(7):2642-4. doi: 10.1128/JCM.00430-06.

Authors

Tristan Ferry¹, Michèle Bes, Olivier Dauwalder, Hélène Meugnier, Gerard Lina, Françoise Forey, François Vandenesch, Jerome Etienne

Affiliation

¹ Centre National de Référence des Staphylocoques, INSERM E0230, IFR 62, Faculté de Médecine Laennec, 7 rue Guillaume Paradin, 69008 Lyon, France. [email protected]

Abstract

The methicillin-resistant Staphylococcus aureus (MRSA) Lyon clone, detected throughout France, contains the enterotoxin A gene (sea), like other pandemic clones of clonal complex 8 (CC8). The egc locus was detected in MRSA pandemic clones of CC5, CC22, and CC45, occasionally with the toxic shock syndrome toxin 1 gene. The representative strain of the EMRSA-16 clone (CC30) harbored both sea and the egc locus.

Publication types

Comparative Study

MeSH terms

Bacterial Toxins / genetics*
Cluster Analysis
DNA, Bacterial / genetics
Electrophoresis, Gel, Pulsed-Field
Enterotoxins / genetics
France
Genes, Bacterial
Humans
Methicillin Resistance*
Polymerase Chain Reaction
Staphylococcus aureus / classification
Staphylococcus aureus / drug effects
Staphylococcus aureus / genetics*
Superantigens / genetics

Substances

Bacterial Toxins
DNA, Bacterial
Enterotoxins
Superantigens
enterotoxin F, Staphylococcal
enterotoxin A, Staphylococcal