Abstract
Myocardial infarction is associated with an immune response. Physiological inflammation response causes self-repair and protection, while pathological autoimmune response leads to ventricular remodeling and heart failure. Laying emphasis on regulating the immune function may become a new target for the prevention of heart failure after myocardial infarction. This review focuses on the mechanism of immune-mediated ventricular remodeling and the immune therapy after myocardial infarction.
MeSH terms
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Animals
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Autoantigens / immunology
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Autoimmunity*
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Cell Differentiation / immunology
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Cell Proliferation
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Heart Failure / immunology
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Heart Failure / prevention & control
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Humans
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Immunity, Cellular
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Immunotherapy
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Inflammation Mediators / metabolism
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Myocardial Infarction / complications
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Myocardial Infarction / immunology*
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Myocardial Infarction / physiopathology
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Myocardial Infarction / therapy
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T-Lymphocytes / immunology
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Ventricular Remodeling / immunology
Substances
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Autoantigens
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Inflammation Mediators