Diterpenes from the Far-eastern brown alga Dictyota dichotoma

Sophia A Kolesnikova; Anatoly I Kalinovsky; Sergei N Fedorov; Larisa K Shubina; Valentin A Stonik

doi:10.1016/j.phytochem.2006.05.041

Diterpenes from the Far-eastern brown alga Dictyota dichotoma

Phytochemistry. 2006 Oct;67(19):2115-9. doi: 10.1016/j.phytochem.2006.05.041. Epub 2006 Jul 13.

Authors

Sophia A Kolesnikova¹, Anatoly I Kalinovsky, Sergei N Fedorov, Larisa K Shubina, Valentin A Stonik

Affiliation

¹ Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, Prospect 100 let Vladivostoku, 690022 Vladivostok, Russia.

PMID: 16842831
DOI: 10.1016/j.phytochem.2006.05.041

Abstract

Two diterpenes, ent-erogorgiaene and (+)-1,5-cyclo-5,8,9,10-tetrahydroerogorgiaene, were isolated from the Russian Far-eastern population of the brown alga Dictyota dichotoma along with three previously known from this alga terpenoids. In addition, pentadecane was the first time isolated as natural product from this species. The structures of all compounds and their stereochemistry were determined using 1D and 2D NMR ((1)H-(1)H COSY, DEPT, HSQC, HMBC and NOESY), mass spectrometry, and optical rotation data.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Line
Cell Line, Tumor
Cell Survival / drug effects
Diterpenes / chemistry*
Diterpenes / isolation & purification
Diterpenes / pharmacology
HeLa Cells
Humans
Inhibitory Concentration 50
Magnetic Resonance Spectroscopy / methods
Molecular Structure
Phaeophyceae / chemistry*
Plant Extracts / chemistry
Sesquiterpenes / chemistry
Sesquiterpenes / isolation & purification
Sesquiterpenes / pharmacology

Substances

Diterpenes
Plant Extracts
Sesquiterpenes