[Fibronectin immunohistochemical staining for diagnosing sudden death caused by viral myocarditis]

Fa Yi Xue Za Zhi. 2006 Apr;22(2):84-5.
[Article in Chinese]

Abstract

Objective: To study the value of Fibronectin(Fn) immunohistochemical staining for diagnosing slight viral myocarditis.

Methods: The heart samples of human with myocarditis were studied by using LSAB immunohistochemical staining with anti-fibronectin antibody.

Results: Dense deposition was found in the myocardium of human with myocarditis. Some Fn-positive cardiomyocytes were observed.

Conclusion: Slight degeneration of cardiomyocytes could be identified by Fn-LSAB immunohistochemical staining and Fn-deposition is one of the reliable marks for inflammation in the myocardium.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Autopsy
  • Death, Sudden / etiology
  • Death, Sudden / pathology
  • Diagnosis, Differential
  • Fibronectins / metabolism*
  • Humans
  • Immunohistochemistry
  • Myocarditis / complications
  • Myocarditis / diagnosis*
  • Myocarditis / virology*
  • Myocardium / metabolism
  • Myocardium / pathology*
  • Staining and Labeling

Substances

  • Fibronectins