Chorea induced by globus pallidus externus stimulation in a dystonic patient

Mov Disord. 2006 Oct;21(10):1771-3. doi: 10.1002/mds.21047.

Abstract

Bilateral high-frequency stimulation of the internal part of the pallidum has proven its efficacy in improving motor symptoms of dystonia. In Parkinson's disease, the stimulation of the external pallidum (GPe) can induce dyskinesias. This has never been described in dystonia. We report here a case of abnormal movements induced by the stimulation of GPe in a dystonic patient and discuss the pathophysiological mechanisms.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antipsychotic Agents / adverse effects*
  • Chorea / etiology*
  • Chorea / physiopathology*
  • Deep Brain Stimulation / adverse effects*
  • Dominance, Cerebral / physiology
  • Dyskinesia, Drug-Induced / therapy*
  • Dystonia / chemically induced*
  • Dystonia / therapy*
  • Electrodes, Implanted
  • Female
  • Globus Pallidus / physiopathology*
  • Humans
  • Magnetic Resonance Imaging
  • Treatment Outcome

Substances

  • Antipsychotic Agents