Pediatric multiple sclerosis: detection of clinically silent lesions by multimodal evoked potentials

Daniela Pohl; Kevin Rostasy; Stephanie Treiber-Held; Knut Brockmann; Jutta Gärtner; Folker Hanefeld

doi:10.1016/j.jpeds.2006.01.003

Pediatric multiple sclerosis: detection of clinically silent lesions by multimodal evoked potentials

J Pediatr. 2006 Jul;149(1):125-7. doi: 10.1016/j.jpeds.2006.01.003.

Authors

Daniela Pohl¹, Kevin Rostasy, Stephanie Treiber-Held, Knut Brockmann, Jutta Gärtner, Folker Hanefeld

Affiliation

¹ Department of Pediatrics and Pediatric Neurology, Georg August University Goettingen, Germany. [email protected]

PMID: 16860140
DOI: 10.1016/j.jpeds.2006.01.003

Abstract

Pediatric patients with multiple sclerosis (MS) frequently do not meet MRI criteria for diagnosis because of lack of evidence of dissemination in space. We assessed the diagnostic utility of multimodal evoked potentials (EP). In 46% of 85 childhood patients with MS, spatial dissemination was detected by EP before the second clinical attack. EP may constitute an important tool for earlier diagnosis of pediatric MS.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Child
Evoked Potentials / physiology*
Female
Humans
Male
Multiple Sclerosis / diagnosis*
Multiple Sclerosis / physiopathology*
Neurologic Examination
Retrospective Studies