Abstract
Seven open reading frames, annotated as potential penicillin-binding-protein-encoding genes (lmo0441, lmo0540, lmo1438, lmo1892, lmo2039, lmo2229, and lmo2754), were targeted for insertional mutagenesis in Listeria monocytogenes EGDe. These genes were found to contribute in various degrees to beta-lactam resistance, cell morphology, or the virulence potential of this organism.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Colony Count, Microbial
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Genes, Bacterial*
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Listeria monocytogenes / classification
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Listeria monocytogenes / cytology*
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Listeria monocytogenes / genetics*
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Listeria monocytogenes / pathogenicity*
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Listeria monocytogenes / ultrastructure
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Listeriosis / microbiology
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Molecular Sequence Data
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Molecular Weight
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Mutagenesis, Insertional
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Open Reading Frames
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Penicillin-Binding Proteins / genetics
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Penicillin-Binding Proteins / metabolism*
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Penicillin-Binding Proteins / physiology
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Penicillins / metabolism
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Virulence / genetics
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beta-Lactam Resistance / genetics
Substances
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Penicillin-Binding Proteins
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Penicillins