Heterogeneity in drug disposition determines interindividual variability of docetaxel pharmacokinetics

Cancer Biol Ther. 2006 Jul;5(7):840-1. doi: 10.4161/cbt.5.7.3025. Epub 2006 Jul 12.

Authors

William D Figg¹, Cindy H Chau

Affiliation

¹ Molecular Pharmacology Section, Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA. [email protected]

PMID: 16880730
DOI: 10.4161/cbt.5.7.3025

No abstract available

Publication types

Comment

MeSH terms

Antineoplastic Agents, Phytogenic / pharmacokinetics*
Cytochrome P-450 CYP3A / genetics*
Cytochrome P-450 CYP3A / metabolism*
Docetaxel
Humans
Taxoids / pharmacokinetics*

Substances

Antineoplastic Agents, Phytogenic
Taxoids
Docetaxel
Cytochrome P-450 CYP3A