Abstract
Important new polymerase chain reaction-based techniques have been developed to assist in genome analysis. Applications range from genetic and physical mapping of DNA to sequence analysis. The polymerase chain reaction has played a significant role in increasing the feasibility of many aspects of genome analysis and positional cloning.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Animals
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Chromosome Mapping / methods*
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Cloning, Molecular / methods
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DNA Mutational Analysis
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Genetic Markers
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Genetic Vectors
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Genome*
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Genomic Library
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Humans
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Mice
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Polymerase Chain Reaction*
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Polymorphism, Restriction Fragment Length
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Repetitive Sequences, Nucleic Acid
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Saccharomyces cerevisiae
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Sequence Tagged Sites*