Chronic vulvovaginal pruritus treated successfully with GnRH analogue

Postgrad Med J. 2006 Aug;82(970):e22. doi: 10.1136/pgmj.2005.043950.

Abstract

A Medline search shows that this is the first reported case where vulvovaginal pruritus was treated successfully with a GnRH analogue. The report describes a patient with chronic premenstrual vulvovaginal pruritus thought to be attributable to autoimmune progesterone dermatitis.

MeSH terms

  • Adult
  • Antipruritics / therapeutic use*
  • Chronic Disease
  • Female
  • Gonadotropin-Releasing Hormone / analogs & derivatives
  • Humans
  • Leuprolide / therapeutic use*
  • Menstruation Disturbances / chemically induced
  • Menstruation Disturbances / drug therapy*
  • Progesterone / adverse effects
  • Progestins / adverse effects
  • Pruritus / chemically induced
  • Pruritus / drug therapy*
  • Pruritus Vulvae / chemically induced
  • Pruritus Vulvae / drug therapy*
  • Vaginal Diseases / chemically induced
  • Vaginal Diseases / drug therapy*

Substances

  • Antipruritics
  • Progestins
  • Gonadotropin-Releasing Hormone
  • Progesterone
  • Leuprolide