Children born after their fathers had been treated with chemotherapy for testicular cancer

B M van der Kolk; N H Mulder; A Mantingh; E van den Berg; H Schraffordt Koops; E G de Vries; P H Willemse; D T Sleijfer

doi:10.1016/0028-2243(90)90020-2

Children born after their fathers had been treated with chemotherapy for testicular cancer

Eur J Obstet Gynecol Reprod Biol. 1990 Jan-Feb;34(1-2):167-70. doi: 10.1016/0028-2243(90)90020-2.

Authors

B M van der Kolk¹, N H Mulder, A Mantingh, E van den Berg, H Schraffordt Koops, E G de Vries, P H Willemse, D T Sleijfer

Affiliation

¹ Department of Medical Oncology, University Hospital Groningen, The Netherlands.

PMID: 1689259
DOI: 10.1016/0028-2243(90)90020-2

Abstract

Twenty children fathered by 15 patients treated with platinum-based combination chemotherapy for disseminated testicular carcinoma were examined and found to have no evidence of congenital malformations. The results indicate no reason for advising against pregnancies in this group of young couples.

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Bleomycin / therapeutic use
Cisplatin / therapeutic use
Female
Humans
Male
Pregnancy
Pregnancy Outcome*
Testicular Neoplasms / drug therapy*
Vinblastine / therapeutic use

Substances

Bleomycin
Vinblastine
Cisplatin

Supplementary concepts

PVB protocol