Depletion of bone marrow T-lymphocytes with an anti-CD5 monoclonal immunotoxin (ST-1 immunotoxin): effective prophylaxis for graft-versus-host disease

Prog Clin Biol Res. 1990:333:207-15.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Monoclonal / therapeutic use
  • Antigens, CD / immunology
  • Antigens, Differentiation / immunology
  • Bone Marrow / immunology*
  • Bone Marrow Cells
  • Bone Marrow Transplantation / immunology
  • Bone Marrow Transplantation / methods*
  • CD5 Antigens
  • Child
  • Child, Preschool
  • Combined Modality Therapy
  • Cyclophosphamide / therapeutic use
  • Cytarabine / therapeutic use
  • Drug Evaluation
  • Graft vs Host Disease / prevention & control*
  • Humans
  • Immunotoxins / therapeutic use*
  • Leukemia / therapy
  • Middle Aged
  • Myelodysplastic Syndromes / therapy
  • Ricin / therapeutic use*
  • Risk Factors
  • T-Lymphocytes / drug effects
  • T-Lymphocytes / immunology*
  • Whole-Body Irradiation

Substances

  • Antibodies, Monoclonal
  • Antigens, CD
  • Antigens, Differentiation
  • CD5 Antigens
  • Immunotoxins
  • Cytarabine
  • Cyclophosphamide
  • Ricin