Abstract
The past five years have seen a steady accumulation of data reinforcing the view that Rab-regulated recycling pathways contribute to cell migration. In particular, detailed descriptions have emerged of the mechanisms that recruit integrins and growth factor receptors to Rab4- and Rab11-driven pathways. Recent work provides new insight into the importance of particular recycling events in cell migration within a variety of physiological contexts.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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ADP-Ribosylation Factors / metabolism
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Animals
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Cell Membrane / metabolism*
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Cell Movement / physiology*
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Endocytosis / physiology*
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Exocytosis / physiology
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Integrins / metabolism
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Receptors, Chemokine / metabolism
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Receptors, Growth Factor / metabolism
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Signal Transduction / physiology*
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rab GTP-Binding Proteins / metabolism
Substances
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Integrins
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Receptors, Chemokine
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Receptors, Growth Factor
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ADP-Ribosylation Factors
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rab GTP-Binding Proteins