Over the past decade, video-assisted thoracoscopic techniques have been used in the pediatric population. Recently, the computer-enhanced robotic system has been applied to video-assisted thoracoscopic interruption of patent ductus arteriosus (VATS-PDA). We focused on the utility of a voice-controlled robotic arm (automated endoscope system for optimal positioning: AESOP 3000) in VATS-PDA. Thirteen infants weighing 4.2 approximately 12.6 (mean 6.6) kg underwent robotically assisted VATS-PDA. Robotically assisted VATS-PDA is comparable with closure by means of the conventional video-assisted thoracoscopic technique.