Abstract
LMWHs are the major anticoagulant/antithrombotic treatment given to pregnant women to prevent and treat venous thromboembolism despite the absence of specific clinical trials. An emerging indication, the prevention of adverse pregnancy outcomes, is under investigation. During pregnancy, LMWHs seem to be safe and efficient. Some uncertainties remain about the management of rare potential side effects, particularly in the event of heparin intolerance and with cross-reactivity to danaparoid sodium.
MeSH terms
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Abnormalities, Drug-Induced
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Anticoagulants / administration & dosage
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Anticoagulants / adverse effects*
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Contraindications
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Dermatitis, Allergic Contact
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Female
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Fibrinolytic Agents / administration & dosage
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Fibrinolytic Agents / adverse effects*
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Hemorrhage / chemically induced
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Hemorrhage / drug therapy
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Heparin / administration & dosage
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Heparin / adverse effects
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Heparin / immunology
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Humans
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Pregnancy
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Pregnancy Complications, Hematologic / drug therapy*
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Pregnancy Complications, Hematologic / prevention & control*
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Thrombocytopenia / chemically induced
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Thrombophilia / drug therapy*
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Thrombophilia / prevention & control*
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Venous Thrombosis / drug therapy
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Venous Thrombosis / prevention & control
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Vitamin K / antagonists & inhibitors
Substances
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Anticoagulants
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Fibrinolytic Agents
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Vitamin K
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Heparin