Abstract
The authors conducted a retrospective and brief prospective study of adverse effects of approximately 350 medications in 44 adults with late-onset Tay-Sachs disease (LOTS). Some medications were relatively safe, whereas others, particularly haloperidol, risperidone, and chlorpromazine, were associated with neurologic worsening.
Publication types
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Clinical Trial
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Analgesics, Non-Narcotic / therapeutic use
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Disease Progression
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Electroconvulsive Therapy / methods
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Female
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Humans
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Male
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Middle Aged
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Prospective Studies
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Psychotropic Drugs / adverse effects*
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Retrospective Studies
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Tay-Sachs Disease / physiopathology*
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Tay-Sachs Disease / therapy*
Substances
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Analgesics, Non-Narcotic
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Psychotropic Drugs