Procedural morbidity and mortality of elective coil treatment of unruptured intracranial aneurysms

AJNR Am J Neuroradiol. 2006 Sep;27(8):1678-80.

Abstract

Background and purpose: To report morbidity, mortality, and angiographic results of elective coiling of unruptured intracranial aneurysms.

Methods: In a 10-year period, 176 unruptured aneurysms in 149 patients were electively treated with detachable coils. Seventy-nine aneurysms were additional to another ruptured aneurysm but were coiled more than 3 months after subarachnoid hemorrhage, 59 aneurysms were incidentally discovered, and 38 aneurysms presented with symptoms of mass effect. Mean size of the 176 unruptured aneurysms was 10.6 mm (median, 8 mm; range, 2-55 mm). One hundred thirteen aneurysms (64%) were small (<10 mm), 44 aneurysms (25%) were large (10-25 mm), and 19 aneurysms (11%) were giant (25-55 mm). Thirty wide-necked aneurysms (17%) were coiled with the aid of a supporting device.

Results: Procedural mortality of coiling was 1.3% (2 of 149; 95% confidence interval [CI], 0.7-5.1%), and morbidity was 2.6% (4 of 149, 95% CI, 0.8-7.0%). The 4 patients with permanent morbidity were independent (GOS 4). Initial aneurysm occlusion was complete (100%) in 132 aneurysms, nearly complete (90%-98%) in 36 aneurysms, and incomplete (60%-85%) in 8 aneurysms. Six-month follow-up angiography was available in 132 patients with 154 coiled aneurysms (87.5%); partial reopening occurred in 25, mainly large and giant aneurysms (16.2%). Additional coiling was performed in 22 aneurysms and additional parent vessel occlusion in 1 aneurysm. There were no complications of additional treatments.

Conclusion: Elective coiling of unruptured intracranial aneurysms has low procedural mortality and morbidity. For the management of unruptured aneurysms, endovascular treatment should be considered.

MeSH terms

  • Adolescent
  • Adult
  • Aneurysm, Ruptured / diagnostic imaging
  • Aneurysm, Ruptured / mortality*
  • Aneurysm, Ruptured / therapy*
  • Brain Damage, Chronic / mortality
  • Cerebral Angiography
  • Elective Surgical Procedures
  • Embolization, Therapeutic / mortality*
  • Hospital Mortality
  • Humans
  • Incidental Findings
  • Intracranial Aneurysm / diagnostic imaging
  • Intracranial Aneurysm / mortality*
  • Intracranial Aneurysm / therapy*
  • Middle Aged
  • Neurologic Examination
  • Retrospective Studies
  • Subarachnoid Hemorrhage / diagnostic imaging
  • Subarachnoid Hemorrhage / mortality
  • Subarachnoid Hemorrhage / therapy
  • Survival Rate
  • Treatment Outcome