The human PDGF receptor alpha-subunit gene maps to chromosome 4 in close proximity to c-kit

Hum Genet. 1990 Aug;85(3):383-5. doi: 10.1007/BF00206767.

Abstract

The gene encoding the alpha-subunit of the human platelet-derived growth factor receptor (PDGFRA) maps to band q11-q12 of chromosome 4 by in situ hybridization, which was confirmed by Southern analysis of a Chinese hamster x human cell hybrid that retains only human chromosome 4.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Blotting, Southern
  • Chromosome Mapping
  • Chromosomes, Human, Pair 4*
  • Cricetinae
  • Humans
  • Hybrid Cells
  • Nucleic Acid Hybridization
  • Platelet-Derived Growth Factor*
  • Proto-Oncogene Proteins / genetics
  • Proto-Oncogene Proteins c-kit
  • Receptors, Cell Surface / genetics*
  • Receptors, Platelet-Derived Growth Factor

Substances

  • Platelet-Derived Growth Factor
  • Proto-Oncogene Proteins
  • Receptors, Cell Surface
  • Proto-Oncogene Proteins c-kit
  • Receptors, Platelet-Derived Growth Factor