Stimulatory autoantibodies to the PDGF receptor in scleroderma

N Engl J Med. 2006 Sep 21;355(12):1278-9; author reply 1279-80. doi: 10.1056/NEJMc061927.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Autoantibodies / physiology*
  • Autoimmune Diseases / drug therapy*
  • Benzamides
  • Fibroblasts
  • Gene Expression Regulation
  • Genes, ras
  • Humans
  • Imatinib Mesylate
  • Phenotype
  • Piperazines / therapeutic use*
  • Protein-Tyrosine Kinases / antagonists & inhibitors*
  • Pyrimidines / therapeutic use*
  • Reactive Oxygen Species / metabolism
  • Receptors, Platelet-Derived Growth Factor / antagonists & inhibitors
  • Receptors, Platelet-Derived Growth Factor / immunology*
  • Scleroderma, Systemic / drug therapy*
  • Scleroderma, Systemic / immunology
  • Signal Transduction

Substances

  • Autoantibodies
  • Benzamides
  • Piperazines
  • Pyrimidines
  • Reactive Oxygen Species
  • Imatinib Mesylate
  • Protein-Tyrosine Kinases
  • Receptors, Platelet-Derived Growth Factor