Malignant solitary fibrous tumor originating from the peritoneum and review of the literature

Med Sci Monit. 2006 Oct;12(10):CS95-8. Epub 2006 Sep 25.

Abstract

Background: Solitary fibrous tumor (SFT) is a rare neoplasm frequently involving the pleura. Benign and malignant forms of the tumor occur, the benign variant being three to four times more common than the malignant.

Case report: We present herein a rare case of large malignant solitary fibrous tumor (SFT) originating from the peritoneum. An abdominal computed tomography scan revealed a well-defined solid tumor with mixed density. An abdominal ultrasonography (US) revealed a well-circumscribed solid tumor containing a partially cystic lesion. T1-weighted abdominal magnetic resonance imaging demonstrated a hypo- to isointensity, which was a hypo- to hyperintensity on T2-weighted images. Liposarcoma originating from the retroperitoneum was suggested, and the patient underwent a complete resection of the tumor as well as the left kidney because tumor invasion of the upper left kidney was suspected. Immunohistochemically, the spindle-shaped cells were positive for CD34, and the diagnosis was SFT originating from the peritoneum. At the 14-month follow-up evaluation, no recurrence or metastasis was detected.

Conclusions: This case gave us some difficulty, and the correct diagnosis of the peritoneal mass was valuable. To diagnose the malignant potential of this type of tumor accurately may have value to direct the appropriate therapeutic operations after surgery and postoperative progress observation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antigens, CD34 / metabolism
  • Female
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Neoplasms, Fibrous Tissue / chemistry
  • Neoplasms, Fibrous Tissue / diagnosis*
  • Neoplasms, Fibrous Tissue / metabolism
  • Neoplasms, Fibrous Tissue / pathology*
  • Neoplasms, Fibrous Tissue / surgery
  • Peritoneal Neoplasms / chemistry
  • Peritoneal Neoplasms / diagnosis*
  • Peritoneal Neoplasms / metabolism
  • Peritoneal Neoplasms / pathology*
  • Peritoneal Neoplasms / surgery
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Antigens, CD34