Successful treatment with oral valganciclovir in immunocompetent infant with gastrointestinal manifestations of cytomegalovirus infection

P S Buonuomo; P Maurizi; P Valentini; S Mastrangelo; I Lazzareschi; V Ridola; R Riccardi

doi:10.1038/sj.jp.7211578

Successful treatment with oral valganciclovir in immunocompetent infant with gastrointestinal manifestations of cytomegalovirus infection

J Perinatol. 2006 Oct;26(10):648-9. doi: 10.1038/sj.jp.7211578.

Authors

P S Buonuomo¹, P Maurizi, P Valentini, S Mastrangelo, I Lazzareschi, V Ridola, R Riccardi

Affiliation

¹ Division of Pediatric Oncology, Department of Paediatrics, Università Cattolica del Sacro Cuore, Policlinico A Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy. [email protected]

PMID: 17006527
DOI: 10.1038/sj.jp.7211578

Abstract

A 3-month-old male infant was admitted to hospital with anemia. Follow-up controls revealed the presence of specific cytomegalovirus (CMV) antibodies. Virus was isolated from urine, blood, and saliva. At 7 months of age, he presented with melena. Polymerase chain reaction (PCR) of biopsy samples from the duodenum was positive for CMV. Anemia resolved after starting antiviral therapy with oral valganciclovir.

Publication types

Case Reports

MeSH terms

Anemia / virology*
Antiviral Agents / therapeutic use*
Cytomegalovirus / isolation & purification*
Cytomegalovirus Infections / drug therapy*
Diagnosis, Differential
Ganciclovir / analogs & derivatives*
Ganciclovir / therapeutic use
Humans
Infant
Male
Melena / virology
Valganciclovir

Substances

Antiviral Agents
Valganciclovir
Ganciclovir