Abstract
Acanthosis nigricans was observed 3 months after single lung transplantation in a 51-year-old African American woman with idiopathic pulmonary fibrosis. The patient had no endocrinological abnormalities and was not taking any medications known to cause acanthosis nigricans; extensive investigation did not reveal an underlying malignant process. Because acanthosis nigricans may occur as a paraneoplastic phenomenon, it is important to rule out an underlying malignancy. This is especially important in solid-organ transplant recipients receiving chronic immunosuppressive therapy.
MeSH terms
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Acanthosis Nigricans / diagnosis
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Acanthosis Nigricans / epidemiology
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Acanthosis Nigricans / etiology*
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Black or African American / statistics & numerical data
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Diagnosis, Differential
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Eyelid Diseases / diagnosis
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Eyelid Diseases / epidemiology
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Eyelid Diseases / etiology
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Female
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Hand Dermatoses / diagnosis
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Hand Dermatoses / epidemiology
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Hand Dermatoses / etiology
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Humans
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Immunosuppressive Agents / adverse effects
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Lung Transplantation / adverse effects*
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Lung Transplantation / immunology
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Middle Aged
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Obesity / complications
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Paraneoplastic Syndromes / diagnosis
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Paraneoplastic Syndromes / etiology
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Pulmonary Fibrosis / surgery
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Risk Factors