Pacemaker infection due to Mycobacterium fortuitum: the role of universal 16S rRNA gene PCR and sequencing

Maddalena Giannella; Maricela Valerio; Juan Antonio Franco; Mercedes Marin; Emilio Bouza; Patricia Muñoz

doi:10.1016/j.diagmicrobio.2006.08.010

Pacemaker infection due to Mycobacterium fortuitum: the role of universal 16S rRNA gene PCR and sequencing

Diagn Microbiol Infect Dis. 2007 Mar;57(3):337-9. doi: 10.1016/j.diagmicrobio.2006.08.010. Epub 2006 Oct 3.

Authors

Maddalena Giannella¹, Maricela Valerio, Juan Antonio Franco, Mercedes Marin, Emilio Bouza, Patricia Muñoz

Affiliation

¹ Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.

PMID: 17020794
DOI: 10.1016/j.diagmicrobio.2006.08.010

Abstract

Rapidly growing mycobacteria are a rare cause of pacemaker infection. A low index of suspicion and conventional diagnostic methods may delay diagnosis. We present a review of the literature and report a case of pacemaker infection due to Mycobacterium fortuitum rapidly detected by universal 16S rRNA gene polymerase chain reaction and sequencing.

Publication types

Case Reports
Research Support, Non-U.S. Gov't
Review

MeSH terms

Aged, 80 and over
DNA, Bacterial / analysis
DNA, Bacterial / genetics
Female
Humans
Mycobacterium Infections, Nontuberculous / diagnosis
Mycobacterium Infections, Nontuberculous / genetics*
Mycobacterium fortuitum / genetics*
Mycobacterium fortuitum / pathogenicity*
Pacemaker, Artificial / microbiology*
Polymerase Chain Reaction
RNA, Ribosomal, 16S / classification*
Sequence Analysis, DNA

Substances

DNA, Bacterial
RNA, Ribosomal, 16S